Product Description: Staurosporine (AM-2282) (GMP) is Staurosporine (HY-15141) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases[1][2][3][4][5].
Formula: C28H26N4O3
References: [1]Ganapathy PS, et al. Sensitivity of staurosporine-induced differentiated RGC-5 cells to homocysteine. Curr Eye Res. 2010 Jan;35(1):80-90./[2]Pregi N, et al. Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells. Biochim Biophys Acta. 2006 Feb;1763(2):238-46./[3]Hajimu MORIOKA, et al. Staurosporine-induced Differentiation in a Human Neuroblastoma Cell Line, NB-1. Agricultural and Biological Chemistry. 1985; 1959-1963./[4]Okazaki T, et al. Staurosporine, a novel protein kinase inhibitor, enhances HL-60-cell differentiation induced by various compounds. Exp Hematol. 1988 Jan;16(1):42-8. /[5]Yuste VJ, et al. The prevention of the staurosporine-induced apoptosis by Bcl-X(L), but not by Bcl-2 or caspase inhibitors, allows the extensive differentiation of human neuroblastoma cells. J Neurochem. 2002 Jan;80(1):126-39.
CAS Number: 62996-74-1
Molecular Weight: 466.53
Research Area: Cancer; Infection
Solubility: 10 mM in DMSO
Target: PKC
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