Formulation: A solid
Formal Name: (2R,3R,4S,16S,17R,18R)-3,18-diethyl-1,2,3,4,5,15,16,17,18,19,22,24-dodecahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid, hydrochloride
Purity: ≥95% (mixture of isomers)
Formula Markup: C33H46N4O6 • XHCl
Formula Weight: 594,8
Shelf life (days): 1460
CAS Number: 5370-34-3
Notes: Stercobilin is a fecal pigment and a metabolite of the heme catabolite bilirubin (Item No. 17161).{68032} It induces DNA damage in a comet assay in HepG2 cells when used at concentrations ranging from 0.5 to 17 µM.{68033} Stercobilin (20 and 30 µM) induces activation of NF-κB in a reporter assay and increases the expression of the genes encoding TNF-α, IL-1β, IL-6, inducible nitric oxide synthase (iNOS), and COX-2 in RAW 264.7 macrophages.{68034} Fecal and plasma levels of stercobilin are increased in ob/ob mice.
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