Formulation: A solid
Formal Name: 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-benzene-2,3,5,6-d4-sulfonamide
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C12H10D4N4O2S
Formula Weight: 282,4
Shelf life (days): 1460
CAS Number: 1020719-82-7
Notes: Sulfamethazine-d4 is intended for use as an internal standard for the quantification of sulfamethazine (Item No. 20976) by GC- or LC-MS. Sulfamethazine is a sulfonamide antibiotic.{33013,36441} It inhibits dihydropteroate synthase (DHPS; IC50 = 5.7 µM for the T. gondii enzyme). Sulfamethazine is active against A. pleuropneumoniae (MIC = 32 µg/ml) and enhances the antibacterial activity of trimethoprim (Item No. 16473) against E. coli.{61933,61934} It has been detected in environmental water samples.{37115,37042} Formulations containing sulfamethazine have been used in the treatment of bacterial infections in livestock.
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