TCID , CAS 30675-13-9

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Applications: Useful for cell-based and in vitro studies of UCH-L3 function.

CAS Number: 30675-13-9

Description: A potent and selective inhibitor of ubiquitin C-terminal hydrolase L3 (UCH-L3) (IC50 = 0.6 µM). Inhibits ubiquitin C-terminal hydrolase L1 (UCH-L1) only at higher concentrations (IC50 = 75 µM).

Format: White powder

Purity: ≥97% by TLC.

Solubility: Soluble in DMSO (25 mg/ml)

Warnings: Protect from moisture.

Biosafety Level: Not applicable (BSL-1)

References: 1. Love, K.R. et al. Mechanisms, biology and inhibitors of deubiquitinating enzymes. Nat. Chem. Biol. 2007. 3:697.
2. Mtango, N.R. et al. Essential role of ubiquitin C-terminal hydrolases UCHL1 and UCHL3 in mammalian oocyte maturation. J. Cell Physiol. 2012. 227:2022.

• SKU: BPS27720-2
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 27720-2
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK