Val-Cit-PAB-MMAE (GMP), CAS 644981-35-1

Product Description: Val-Cit-PAB-MMAE GMP is a GMP grade Val-Cit-PAB-MMAE (HY-100374). Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE (HY-15162). MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization.

Applications: Cancer-programmed cell death

Formula: C58H94N10O12

References: [1]Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.

CAS Number: 644981-35-1

Molecular Weight: 1123.43

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-100374G-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-100374G-0
• Package Unit: Get quote
• Quantity Unit: STK