Formulation: A solution in chloroform
Formal Name: butanoic acid, 3-methyl-1′-[(1S,2′R,6S,7aS)-4-[(acetyloxy)methyl]-6,7a-dihydrospiro[cyclopenta[c]pyran-7(1H),2′-oxirane]-1,6-diyl]ester
Purity: ≥98%
Formula Markup: C22H30O8
Formula Weight: 422,5
Shelf life (days): 365
CAS Number: 18296-44-1
Notes: Valtrate is a valepotriate that has been found in Valeriana and has diverse biological activities.{31362,61169,66037} It inhibits nuclear export of influenza virus ribonucleoprotein complex (vRNP) in HeLa cells when used at a concentration of 3.6 µM and inhibits influenza virus infection in MDCK cells (IC50 = 0.19 µM).{31362} Valtrate is cytotoxic to GLC-4 lung and COLO 320 colorectal cancer cells (IC50s = 1.4 and 3 µM, respectively).{61169} It increases the number of entries into, and percentage of time spent in, the open arms of the elevated plus maze, indicating anxiolytic-like activity, and decreases serum corticosterone levels in rats when administered at a dose of 10 mg/kg.{66037}
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