VcMMAE, CAS 646502-53-6

Formulation: A solid

Formal Name: N-[[[4-[[N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide

Purity: ≥98%

Formula Markup: C68H105N11O15

Formula Weight: 1316,6

Shelf life (days): 1460

CAS Number: 646502-53-6

Notes: VcMMAE is a drug-linker molecule that has been used in the synthesis of antibody-drug conjugates (ADCs).{67089},{67090} It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody, a protease-cleavable peptide linker, and the antimitotic and anticancer agent monomethyl auristatin E (MMAE; Item No. 16267).

• SKU: CAY35646-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35646-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK
• Application: Reinstoffe