Formulation: A solid
Formal Name: 5-amino-1-(2,4-dimethoxyphenyl)-1,2-dihydro-4-(4-methyl-2-thiazolyl)-3H-pyrrol-3-one
Purity: ≥95%
Formula Markup: C16H17N3O3S
Formula Weight: 331,4
Shelf life (days): 1095
CAS Number: 951945-67-8
Notes: viFSP1 is a species-independent inhibitor of ferroptosis suppressor protein 1 (FSP1; IC50s = 34 and 83 nM for the human and mouse enzymes, respectively).{68672} It induces ferroptosis in glutathione peroxidase 4 (Gpx4) knockout Pfa1 mouse embryonic fibroblasts expressing human or mouse FSP1, an effect that can be reversed by the ferroptosis inhibitor liproxstatin-1 (Item No. 17730).