Wnt-C59 (GMP), CAS 1243243-89-1

Product Description: Wnt-C59 (C59) GMP is a GMP grade Wnt-C59 (HY-15659). Wnt-C59 (C59) is a highly potent and oral porcupine (PORCN) inhibitor with an IC50 of 74 pM.

Applications: Cancer-programmed cell death

Formula: C25H21N3O

References: [1]Proffitt KD, et al. Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer. Cancer Res. 2013 Jan 15;73(2):502-7./[2]Cheng Y, et al. Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment. Oncotarget. 2015 Jun 10;6(16):14428-39.

CAS Number: 1243243-89-1

Molecular Weight: 379.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Porcupine;Wnt

• SKU: MEXHY-15659G-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15659G-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK