YQ-128, CAS 2454246-18-3

Formulation: A crystalline solid

Formal Name: N-[(5-chloro-2-propoxyphenyl)methyl]-N-[2-[4-[(2-propyn-1-ylamino)sulfonyl]phenyl]ethyl]-3-thiopheneacetamide

Purity: ≥98%

Formula Markup: C27H29ClN2O4S2

Formula Weight: 545,1

Shelf life (days): 1460

CAS Number: 2454246-18-3

Notes: YQ-128 is an inhibitor of the NOD-like receptor protein 3 (NLRP3) inflammasome (IC50 = 0.3 µM).{62631} It inhibits LPS- and ATP-induced IL-1β release from isolated mouse peritoneal macrophages (IC50 = 1.59 µM). YQ-128 (10 mg/kg) inhibits LPS-induced IL-1β production in wild-type but not Nlrp3-/- mice.

• SKU: CAY36451-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36451-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe