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Amino Acid Sequence: Z-Phe-Ala-CH2F
Biological Activity: We recommend using 2-10 µM for inhibiting non-caspase cysteine protease activity in cell culture, or as a control for other FMK caspase inhibitors. The optimal dose may vary for different cells and culture conditions.
CAS Number: 197855-65-5
Purity: ≥95% by HPLC
Solubility: Soluble in DMSO
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Target: cathepsins
Biosafety Level: Not applicable (BSL-1)
References: 1. Lopez-Hernandez, F.J., et al. 2003. Mol. Cancer Ther. 2: 255-263.
2. Ahmed, N.K., et al. 1992. Biochem. Pharmacol: 44: 1201-1207.
3. Lawrence, C.P., et al. 2006. J. Immunol. 177: 3827-3826.
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