Product Description: 1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba
Applications: Cancer-programmed cell death
Formula: C17H12
References: [1]Monien BH, et al. Time course of hepatic 1-methylpyrene DNA adducts in rats determined by isotope dilution LC-MS/MS and 32P-postlabeling. Chem Res Toxicol. 2008 Oct;21(10):2017-25. /[2]Hang Yu, et al. 1-Methylpyrene induces chromosome loss and mitotic apparatus damage in a Chinese hamster V79-derived cell line expressing both human CYP1A2 and sulfotransferase 1A1. Chem Biol Interact. 2020 Dec 1;332:109283.
CAS Number: 2381-21-7
Molecular Weight: 216.28
Compound Purity: 99.51
Research Area: Others
Solubility: DMSO : 4.35 mg/mL (ultrasonic;warming;heat to 60°C)