Product Description: 4-Azido-2,3,5,6-tetrafluorobenzoic Acid (N3-TFBA) is a click chemistry reagent containing an azide group. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid is a complex with FAM-labeled DNA probe. 4-Azido-2,3,5,6-tetrafluorobenzoic Acid can be used as versatile photoaffinity labeling agents to probe biological receptors. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Applications: Cancer-programmed cell death
Formula: C7HF4N3O2
References: [1]Li G, et al. Multivalent photoaffinity probe for labeling small molecule binding proteins. Bioconjug Chem. 2014 Jun 18;25(6):1172-80.
CAS Number: 122590-77-6
Molecular Weight: 235.10
Research Area: Others
Solubility: 10 mM in DMSO
Target: ADC Linker
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