6,7-Dihydroxy-4-coumarinylacetic acid, CAS 88404-14-2

Product Description: 6,7-Dihydroxy-4-coumarinylacetic acid is a potent and selective inhibitor of ALR2. 6,7-Dihydroxy-4-coumarinylacetic acid inhibits ALR2, SDH andALR1 with IC50s of 9.6, 288 and 66.3 μM, respectively. 6,7-Dihydroxy-4-coumarinylacetic acid clearly suppresses galactitol accumulation[1].

Formula: C11H8O6

References: [1]Kato A, et al. 6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5630-3.

CAS Number: 88404-14-2

Molecular Weight: 236.18

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Aldose Reductase

• SKU: MEXHY-D0064-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-D0064-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK