Product Description: 7-Aminoactinomycin D (7-AAD) a fluorescent DNA stain, is a potent RNA polymerase inhibitor. 7-Aminoactinomycin D selectively binds to GC regions of the DNA. 7-Aminoactinomycin D also has antibacterial effects[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C62H87N13O16
References: [1]Wadkins RM, et al. Actinomycin D and 7-aminoactinomycin D binding to single-stranded DNA. Biochemistry. 1991 Oct 1;30(39):9469-78./[2]Nadine C L Zembruski, et al. 7-Aminoactinomycin D for apoptosis staining in flow cytometry. Anal Biochem. 2012 Oct 1;429(1):79-81./[3]Hanen Sellami, et al. Molecular detection of Chlamydia trachomatis and other sexually transmitted bacteria in semen of male partners of infertile couples in Tunisia: the effect on semen parameters and spermatozoa apoptosis markers. PLoS One. 2014 Jul 14;9(7):e98903.
CAS Number: 7240-37-1
Molecular Weight: 1270.43
Compound Purity: 99.0
Research Area: Cancer; Infection
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Antibiotic;Bacterial;DNA Stain;DNA/RNA Synthesis
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