8RK59, CAS 2705841-53-6

Product Description: 8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC50 close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59[1].

Formula: C33H39BF2N10O2S

References: [1]Kooij R, et al. Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos. J Am Chem Soc. 2020 Sep 30;142(39):16825-16841.

CAS Number: 2705841-53-6

Molecular Weight: 688.60

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Deubiquitinase

• SKU: MEXHY-D1726-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-D1726-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK