Product Description: Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B[1].
Formula: C31H38F3N5O12
References: [1][1]Kazimierz Weglarczyk, et al. Caspase-8 activation precedes alterations of mitochondrial membrane potential during monocyte apoptosis induced by phagocytosis and killing of Staphylococcus aureus. Infect Immun. 2004 May;72(5):2590-7. /[2]Przemysław Reszka, et al. Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates. ChemMedChem. 2010 Jan;5(1):103-17.
CAS Number: 211990-57-7
Molecular Weight: 729.65
Compound Purity: 99.91
Research Area: Others
Solubility: DMSO : 125 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic)
Target: Caspase