Product Description: Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is used in making Azure eosin stains for blood smear staining. Azure B is a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. Azure B possesses significant antidepressant-like effects[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C15H16ClN3S
References: [1]Löhr W,et al. The azure dyes: their purification and physicochemical properties. II. Purification of azure B. Stain Technol. 1975 May;50(3):149-56./[2]Delport A, et al. Azure B and a synthetic structural analogue of methylene blue, ethylthioninium chloride, present with antidepressant-like properties. Life Sci. 2014 Nov 11;117(2):56-66.
CAS Number: 531-55-5
Molecular Weight: 305.83
Compound Purity: 96.08
Research Area: Neurological Disease
Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Monoamine Oxidase
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