Product Description: Coelenterazine h (2-Deoxycoelenterazine), a coelenterazine derivative, is a luminescent substrate for RLuc8. Coelenterazine h is more sensitive to Ca2+, thus providing a valuable tool for measuring small changes in Ca2+ concentrations[1][2][3][4].
Applications: Neuroscience-Neuromodulation
Formula: C26H21N3O2
References: [1]M R Knight, et al. Imaging calcium dynamics in living plants using semi-synthetic recombinant aequorins. J Cell Biol. 1993 Apr;121(1):83-90. /[2]Kazushi Suzuki, et al. Five colour variants of bright luminescent protein for real-time multicolour bioimaging. Nat Commun. 2016 Dec 14:7:13718. /[3]Kenta Saito, et al. Auto-luminescent genetically-encoded ratiometric indicator for real-time Ca2+ imaging at the single cell level. PLoS One. 2010 Apr 1;5(4):e9935./[4]Jiang T, et al. New bioluminescent coelenterazine derivatives with various C-6 substitutions. Org Biomol Chem. 2017 Aug 23;15(33):7008-7018.
CAS Number: 50909-86-9
Molecular Weight: 407.46
Compound Purity: 98.02
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Biochemical Assay Reagents;Calcium Channel
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