Product Description: DAPI dihydrochloride is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells[1].
Formula: C16H17Cl2N5
References: [1]Kapuscinski J, et al. DAPI: a DNA-specific fluorescent probe. Biotech Histochem. 1995 Sep;70(5):220-33.
CAS Number: 28718-90-3
Molecular Weight: 350.25
Compound Purity: 99.67
Research Area: Others
Solubility: DMSO : 75 mg/mL (ultrasonic)/H2O : 5.56 mg/mL (ultrasonic;warming;heat to 60°C)
Target: DNA Stain
English
Deutsch
