Product Description: Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I[1][2][3].
Formula: N/A
References: [1]Malcolm E. Bergy et al. Filipin complex. Biochemistry, 1968, 7, 2, 653-659./[2]Houdai T, et al. Membrane-permeabilizing activities of amphidinol 3, polyene-polyhydroxy antifungal from a marine dinoflagellate. Biochim Biophys Acta. 2004 Nov 17;1667(1):91-100./[3]Huang L, et al. Role of lipid rafts in porcine reproductive and respiratory syndrome virus infection in MARC-145 cells. Biochem Biophys Res Commun. 2011 Oct 28;414(3):545-50.
CAS Number: 11078-21-0
Molecular Weight: N/A
Compound Purity: 97.68
Research Area: Infection
Solubility: DMSO : ≥ 100 mg/mL/Ethanol : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Antibiotic;Fungal
English
Deutsch
