Formulation: A solid
Formal Name: (E)-4-(4-(2-(1-ethyl-3,3-dimethylindolin-2-yl)vinyl)phenyl)morpholine
Purity: ≥98%
Formula Markup: C24H30N2O
Formula Weight: 362,5
Shelf life (days): 730
Notes: HCy-Lyso is a lysosome-specific fluorescent reporter for the detection of hydroxyl radicals.{67822} It selectively fluoresces in low pH environments in the presence of hydroxy radicals over hypochlorite, superoxide, nitric oxide, or peroxynitrite radicals. HCy-Lyso (10 µM) displays lysosomal fluorescence in the presence of the ferroptosis inducers erastin (Item No. 17754) or (1S,3R)-RSL3 (Item No. 19288), an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 (Item No. 17729), in 4T1 cells. HCy-Lyso displays excitation/emission maxima of 510/592 nm, respectively, in low pH environments in the presence of hydroxy radicals.
English
Deutsch
