Product Description: Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
Formula: C16H14O6
References: [1]Robert D Cardiff, et al. Manual hematoxylin and eosin staining of mouse tissue sections. Cold Spring Harb Protoc. 2014 Jun 2;2014(6):655-8./[2]M Titford. The long history of hematoxylin. Biotech Histochem. Mar-Apr 2005;80(2):73-8./[3]Yilong Tu, et al. Hematoxylin Inhibits Amyloid β-Protein Fibrillation and Alleviates Amyloid-Induced Cytotoxicity. J Phys Chem B. 2016 Nov 10;120(44):11360-11368./[4]Ada T Feldman, et al. Tissue processing and hematoxylin and eosin staining. Methods Mol Biol. 2014;1180:31-43.
CAS Number: 517-28-2
Molecular Weight: 302.28
Compound Purity: 98.02
Research Area: Others
Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : 6.67 mg/mL (ultrasonic)
Target: Amyloid-β
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