Product Description: NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O2-. O2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model[1].
Applications: Neuroscience-Neuromodulation
Formula: C20H17F3N2O3S
References: [1]Yang W, et al. Novel Near-Infrared Fluorescence Probe for Bioimaging and Evaluating Superoxide Anion Fluctuations in Ferroptosis-Mediated Epilepsy. Anal Chem. 2023 Aug 22;95(33):12240-12246..
Molecular Weight: 422.42
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Fluorescent Dye
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