Product Description: Procion Blue HB (Reactive Blue 2) is a purinergic antagonist.
Applications: COVID-19-immunoregulation
Formula: C29H20ClN7O11S3
References: [1]Okuda A, et al. Reactive blue 2 induces calcium oscillations in HeLa cells. Jpn J Physiol. 2001 Jun;51(3):389-93./[2]Lee JH, et al. Reactive blue 2, an antagonist of rat P2Y4, increases K+ secretion in rat cochlea strial marginal cells. Hear Res. 2006 Sep;219(1-2):66-73./[3]Coughlan SJ, et al. Reactive blue 2 is a potent inhibitor of a thylakoid protein kinase. Eur J Biochem. 1991 Apr 23;197(2):467-71./[4]Burnstock G, et al. P2-purinoceptors of two subtypes in the rabbit mesenteric artery: reactive blue 2 selectively inhibits responses mediated via the P2y-but not the P2x-purinoceptor. Br J Pharmacol. 1987 Feb;90(2):383-91./[5]Uneyama H, et al. Suramin and reactive blue 2 are antagonists for a newly identified purinoceptor on rat megakaryocyte. Br J Pharmacol. 1994 Jan;111(1):245-9.
CAS Number: 12236-82-7
Molecular Weight: 774.16
Compound Purity: 95.0
Research Area: Neurological Disease; Cardiovascular Disease
Solubility: DMSO : ≥ 110 mg/mL/Ethanol : 1 mg/mL (ultrasonic)/H2O : 10 mg/mL (ultrasonic)
Target: Fluorescent Dye
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