Product Description: QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission[1].
Formula: C29H25N4NaO3S2
References: [1]Wei Fu, Wei-Hong Zhu, et al. Rational Design of Near-Infrared Aggregation-Induced-Emission-Active Probes: In Situ Mapping of Amyloid-β Plaques with Ultrasensitivity and High-Fidelity. J. Am. Chem. Soc. 2019, 141, 7, 3171–3177./[2]Wei Fu, et al. Rational Design of Near-Infrared Aggregation-Induced-Emission-Active Probes: In Situ Mapping of Amyloid-β Plaques with Ultrasensitivity and High-Fidelity. J Am Chem Soc. 2019 Feb 20;141(7):3171-3177.
CAS Number: 2316820-94-5
Molecular Weight: 564.65
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Amyloid-β;Fluorescent Dye
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