Product Description: SiR-Hoechst is a far-red fluorescent DNA probe being used widely for time-lapse imaging of living cells. SiR-Hoechst is minimally toxic at concentrations as high as 10-25 µM. SiR-Hoechst induces DNA damage responses and G2 arrest at concentrations well below 1 µM[1][2].
Formula: C56H59N9O4Si
References: [1]Sen O, et al. The live cell DNA stain SiR-Hoechst induces DNA damage responses and impairs cell cycle progression. Sci Rep. 2018 May 21;8(1):7898./[2]Lukinavičius G, et al. SiR-Hoechst is a far-red DNA stain for live-cell nanoscopy. Nat Commun. 2015 Oct 1;6:8497.