Product Description: Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface[1][2].
Formula: C26H40N5NaO10S2
References: [1]Diaz G, et al. Changes in the Membrane-Associated Proteins of Exosomes Released from Human Macrophages after Mycobacterium tuberculosis Infection. Sci Rep. 2016 Nov 29;6:37975./[2]Gabant G, et al. Assessment of solvent residues accessibility using three Sulfo-NHS-biotin reagents in parallel: application to footprint changes of a methyltransferase upon binding its substrate. J Mass Spectrom. 2008 Mar;43(3):360-70. /[3]Ilia Fishbein, et al. Post-Deployment Modifications of Stent with Endothelial Cells. CARDIOVASCULAR AND PULMONARY DISEASES, 24, SUPPLEMENT 1, S68, MAY 01, 2016.
CAS Number: 194041-66-2
Molecular Weight: 669.74
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Fluorescent Dye
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