Product Description: Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis[1].
Formula: C18H16BrN5S
References: [1]Berridge MV, et al. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev. 2005;11:127-52./[2]Berridge MV, et al. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev. 2005;11:127-52.
CAS Number: 298-93-1
Molecular Weight: 414.32
Compound Purity: 99.84
Research Area: Others
Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)/H2O : 0.88 mg/mL (ultrasonic;warming)
Target: Fluorescent Dye
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