Product Description: Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms[1].
Formula: C25H25ClN2O7
Citations: Adv Mater. 2023 Mar 29;e2211609./Cell Signal. 2020 Nov;75:109733./Exp Eye Res. 2021 May 28;108640./Adv Sci (Weinh). 2023 Jan 15;e2203869./Aquaculture. 5 October 2022, 738900./Autophagy. 2021 Nov;17(11):3592-3606./Basic Res Cardiol. 2024 Jan 2./Biochem Biophys Res Commun. 9 July 2022./Cell Signal. 2023 Nov 13:110969./Endocrinology. 2020 Sep 1;161(9):bqaa119./Int J Mol Sci. 2023 Jul 17, 24(14), 11554./J Thromb Haemost. 2021 Aug 19./Toxicon. 2 July 2022.
References: [1]Crowley LC, et al. Measuring Mitochondrial Transmembrane Potential by TMRE Staining. Cold Spring Harb Protoc. 2016 Dec 1;2016(12):pdb.prot087361./[2]Chowdhury SR, et al. Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep. 2015 Dec 8;36(1):e00286./[3]Monteith A, et al. Imaging of mitochondrial and non-mitochondrial responses in cultured rat hippocampal neurons exposed to micromolar concentrations of TMRM. PLoS One. 2013;8(3):e58059.
CAS Number: 115532-50-8
Molecular Weight: 500.93
Compound Purity: 99.69
Research Area: Others
Solubility: DMSO : 41.67 mg/mL (ultrasonic)
Target: Fluorescent Dye
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