Product Description: WH-15 is a fluorogenic PLC reporter with Km value of 49; 30, 86.1 µM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells[1].
Applications: Cancer-programmed cell death
Formula: C31H43N2O18P3
References: [1]Huang W, et al. A fluorogenic, small molecule reporter for mammalian phospholipase C isozymes. ACS Chem Biol. 2011 Mar 18;6(3):223-8.
CAS Number: 1264748-47-1
Molecular Weight: 824.60
Research Area: Cancer; Neurological Disease
Solubility: 10 mM in DMSO
Target: Phospholipase