Formulation: A crystalline solid
Formal Name: 2,3,5,6-tetrachloro-1,4-benzenediol
Purity: ≥98%
Formula Markup: C6H2Cl4O2
Formula Weight: 247,9
Shelf life (days): 1460
CAS Number: 87-87-6
Notes: Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol.{45068} It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes.{45069} In vivo, TCHQ induces glutathione (GSH) depletion in mouse liver.{45070}