Caspase 6 Activity Assay Kit(Colorimetric Method)

Assay Time: 4-6 hours

Test Principle: Caspase 6, also known as Mch-2, was originally discovered in human Jurkat cells. The precursor of caspase 6 can be cleaved by granzyme B to form an activated caspase 6 dimer, which is found to induce apoptosis. Caspase 6 can cleave PARP and keratin-18, and also cleave Lamin A, a key component protein on the nuclear envelope. Only caspase 6 can cleave Lamin A in the caspase family. This caspase 6 activity assay kit is based on caspase 6 that can catalyze the substrate Ac-VEID-pNA to generate yellow pNA (p-Nitroaniline). The pNA has a strong absorption near 405 nm, The activity of caspase 6 can be calculated by determining the absorbance at 405 nm.

• SKU: ELSE-CK-A386-20
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-CK-A386-20
• Package Unit: 20 Assays
• Quantity Unit: PAK