Formulation: A crystalline solid
Formal Name: (3β)-cholest-5-en-3-ol 3-(hydrogen butanedioate)
Purity: ≥95%
Formula Markup: C31H50O4
Formula Weight: 486,7
Shelf life (days): 1460
CAS Number: 1510-21-0
Notes: Cholesteryl hemisuccinate is a cholesterol ester with anticancer activity.{36854} It inhibits the growth of murine C1498 myeloid and L1210 lymphocytic leukemia cells when used at concentrations of 50 and 150 μM, respectively.{36854} Cholesteryl hemisuccinate acts as an ionizable anionic detergent and is commonly used to stabilize unilamellar vesicles and liposomes.{36855} It has also been used as an emulsifying agent in various vesicular drug delivery systems for anticancer drugs, antibiotics, and oligonucleotides and to solubilize various proteins including chemokine receptor 1 as well as erythrocyte ghosts.{24443,36856,36857}
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