cKK-E12, CAS 1432494-65-9

Formulation: A solution in ethanol

Formal Name: 3,6-bis[4-[bis(2-hydroxydodecyl)amino]butyl]-2,5-piperazinedione

Purity: ≥95%

Formula Markup: C60H120N4O6

Formula Weight: 993,6

Shelf life (days): 730

CAS Number: 1432494-65-9

Notes: cKK-E12 is an ionizable lipomer that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA.{69077,49896} LNPs containing cKK-E12, in combination with L-319 (Item No. 35051), and encapsulating varicella-zoster virus (VZV) mRNA encoding glycoprotein E (gE) increase the lymph node and spleen levels of CD11c+CD80+ and CD11c+CD86+ cells and total serum IgG titers in mice, as well as decrease the number of VZV-induced rashes and the epithelial levels of VZV DNA in a guinea pig model of VZV-induced shingles.{49896}

• SKU: CAY36700-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36700-25
• Package Unit: 25 mg
• Quantity Unit: STK