DSG-PEG(2000), CAS 308805-39-2

Formulation: A solid

Formal Name: α-[2,3-bis[(1-oxooctadecyl)oxy]propyl]-ω-methoxy-poly(oxy-1,2-ethanediyl)

Purity: ≥95%

Formula Markup: (C2H4O)nC40H78O5

Formula Weight: 386,1

Shelf life (days): 1460

CAS Number: 308805-39-2

Notes: DSG-PEG(2000) is a PEGylated derivative of 1,2-distearoyl-sn-glycerol (DSG; Item No. 15079).{65693} It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). LNPs containing DSG-PEG(2000) and encapsulating a toll-like receptor 7 (TLR7) and TLR8 agonist and a peptide antigen each conjugated to poly(L-glutamic acid) (PGA) increase the activation of dendritic cells, macrophages, and B cells in the draining lymph node and dendritic cells and B cells in the spleen in mice compared to the non-LNP-encapsulated PGA-conjugated TLR7/8 agonist and peptide antigen.

• SKU: CAY37800-250
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37800-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK