DSPE-PEG(2000) Maleimide, CAS 185844-12-6

Formulation: A solid

Formal Name: α-[(9R)-6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]-poly(oxy-1,2-ethanediyl)

Purity: ≥90%

Formula Markup: (C2H4O)nC51H92N3O13P

Shelf life (days): 1460

CAS Number: 185844-12-6

Notes: DSPE-PEG(2000) maleimide is a PEGylated derivative of 1,2-distearoyl-rac-3-PE (DSPE). It has been used in the synthesis of lipid nanoparticles (LNPs) for the delivery of siRNA or small molecule anticancer agents in vitro and in vivo.{51868,63292,63293,62394} LNPs containing DSPE-PEG(2000) maleimide and encapsulating siRNAs targeting mRNA encoding p53 and K-RAS induce tumor regression in a PANC-1 pancreatic ductal adenocarcinoma mouse xenograft model.{51868}

• SKU: CAY42013-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42013-25
• Package Unit: 25 mg
• Quantity Unit: STK