Formulation: A solution in chloroform
Purity: ≥98%
Formula Markup: C41H78NO8P (for oleoyl)
Formula Weight: 744
Shelf life (days): 730
CAS Number: 90989-93-8
Notes: Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids.{24442} In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide (AEA; Item No. 90050) and is a source of ethanolamine used in various cellular functions. In E. coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone.{41481} It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA.{41480} This product contains phosphatidylethanolamine molecular species with primarily C18:1, C22:4, C18:0, C20:4, and C22:6 fatty acyl chains. [Matreya, LLC. Catalog No. 1069]
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