Notes: Q1-SM-102 is a cationic quaternary ammonium lipid derivative of the ionizable cationic lipid SM-102 (Item No. 33474) that has been used in the generation of lipid nanoparticles (LNPs) for use in vivo.{51839} LNPs containing Q1-SM-102 and SM-102 as a cationic lipid pair (CLP) and encapsulating mRNA encoding a luciferase reporter induce luciferase expression in the lungs and spleen in mice.