Cedarlane’santi-Mac-2 monoclonal antibody specifically binds the mouse Mac-2 antigen (alsocross reacts with human). The antibody recognizes a 32,000 dalton surfaceantigen found on a subpopulation of mouse macrophages. It reacts withperitoneal exudate macrophages where the exudate is provoked by thioglycollate,protease peptone (20%), macrophages of lymphoid and non-lymphoid tissues,interdigitating dendritic cells and Langerhans cells. Mac-2 is also expressedin the cytoplasm on non-elicited resident macrophages; 5% are stronglyreactive, the remaining 95% show much weaker staining.