Anti-Rat CD4 Purified (Clone W3/25) (mouse IgG1)

Cedarlane’s anti-rat T helper cell monoclonal antibodiesrecognize a determinant on the majority of thymocytes (90-95%), a subset ofperipheral T cells and peritoneal macrophages (1,2,3,10). The antigenrecognized by this clone is a surface glycoprotein of Mr 48 000 - 52 000 and isthe homologue of the human CD4 and the mouse L3/T4 antigen. Clone W3/25 labelsthe rat T helper subset, which mediates the helper activity for B and T cells,graft vs. host (GVH) reactivity and produces IL-2 in the mixed lymphocyte reaction(MLR) (2,4,6). Addition of W3/25 to the MLR, inhibited proliferation and blocksthe production of IL-2 (4,5,6,9).

• SKU: CEDCL003AP-2
• Manufacturer: Cedarlane
• Manufacturer SKU: CL003AP-2
• Green Labware: No
• Package Unit: 500µg
• Quantity Unit: STK
• Reactivity: Rat (Rattus)
• Application: Immunohistochemistry (frozen), Immunohistochemistry (paraffin), Immunoprecipitation, Flow Cytometry, Functional Assay
• Isotype: IgG1
• Host: Mouse