Formula Weight: 0
Shelf life (days): 180
Notes: The Naveni® CD8/MHC-I Atto647N is an in situ proximity ligation assay kit for the detection of the interaction of CD8 and MHC-I. This in situ kit gives a high signal-to-noise ratio and has outstanding specificity. The kit is compatible with immunofluorescence co-staining for visualization of the tumor microenvironment. The kit has been validated on FFPE human tissue samples. Not recommend for mouse tissue. The kit is based on our Naveni™ in situ Proximity Ligation Technology, featuring two Navenibodies linked to proprietary oligo arms.The technology ensures precise and sensitive detection; learn more about Naveni technology. The primary antibodies included in the kit bind to CD8 and MHC-I proteins, while Navenibodies then bind to their respective primary antibodies. When Navenibodies are in close proximity, a strong and distinct signal is generated, offering a specific and sensitive detection method for the interaction between CD8 and MHC-I. Included in the kit: • Primary antibody targeting human CD8 • Primary antibody targeting human MHC-I • Two Navenibodies targeting respectively primary antibody • Detection fluorophore; Atto647N • Buffers for blocking and dilutions, and all detection reagents • The Navenibody solution has a working volume of 4000 µl Tris EDTA antigen retrieval buffer pH 9, wash buffer, DAPI nuclear stain, and mounting medium are not included in the kit.
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