Description of Target: 0
Immunogen: Peptide sequence around phosphorylation site of tyrosine 279/216 (V-S-Y(p)-I-C) derived from Human GSK3α/Β.
Key Reference: Chin PC, et al. Brain Res Mol Brain Res 25 Jun 13; 137(1-2): 193-21
Takahashi-Yanaga F, et al. Biochem Biophys Res Commun 24 Apr 2; 316(2): 411-415
Fan G, et al. J Biol Chem 23 Dec 26; 278(52): 52432-52436
Liao X, et al. Mol Cancer Ther 23 Nov; 2(11): 1215-1222
Product Format:
Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 15mM NaCl, .2% sodium azide and 5% glycerol.
Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Specificity#: The antibody detects endogenous level of GSK3α/β only when phosphorylated at tyrosine 279/216
Tag:
P4984,
P49841
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