Zymo-Seq SPLAT DNA Library Kit

OneStep PCR Inhibitor Removal Kit

Use the promocode EPI20 until December 24th 2024 on your order to get a 20% discount on our research tools for discovering, exploring & mapping the epigenetic landscape! No additional discounts can be applied during the promotion period.

Description: The Zymo-Seq™ SPLAT DNA Library Kit is a versatile solution for DNA library preparation from a wide variety of sample types. By applying the unique, single-stranded library preparation approach of Splinted Ligation Adapter Tagging (SPLAT), DNA libraries can be prepared from genomic DNA, cell-free DNA, and even FFPE-derived DNA with ease. Additionally, the SPLAT technology allows for direct ligation of adapters onto the native ends of each DNA fragment, simultaneously eliminating the need for end-repair and ensuring preservation of all original nucleotides. This feature allows for accurate and high-fidelity analysis of fragmentation patterns, setting a new standard for fragmentomics analysis.
The Zymo-Seq™ SPLAT DNA Library Kit easily generates library from 10 ng to 500 ng of pre-fragmented DNA input in just two simple steps: (a) ligation of the single-stranded DNA with the unique splinted adapters concurrently and (b) amplification of the libraries via PCR using unique dual indexes. By utilizing a straightforward workflow that is efficient and user-friendly, the Zymo-Seq™ SPLAT DNA Library Kit allows for generation of high-quality libraries ready for DNA sequencing in as little as 3 hours.

• Novel Solution for Fragmentomics Analysis: Powered by Splinted Ligation Adapter Tagging (SPLAT) technology, the kit precisely captures the true fragment ends of cell-free DNA, enabling accurate and high-fidelity analysis of fragmentation patterns.
• Versatile Sample Handling: The kit supports a wide range of sample types, including cell-free DNA (cfDNA), FFPE-derived DNA, and genomic DNA, while ensuring true end ligation for reliable and precise genomic data across diverse research applications.
• Efficient Workflow: The two-step workflow allows for the preparation of DNA samples into sequencing-ready libraries in as little as three hours, significantly speeding up the research process.

• SKU: ZYMD5464
• Manufacturer: Zymo Research
• Manufacturer SKU: D5464
• Package Unit: 12 preps
• Quantity Unit: PAK