CRISPR

CRISPR

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) are segments of short, regularly placed palindromic nucleotide repetitions. CAS (CRISPR-Associated Protein) is a CRISPR-associated nuclease enabling controlled DNA cleavage.

CRISPR/Cas9 systems allow for targeted gene editing. Briefly, aCRISPR/Cas9 complex binds to a specific DNA sequence, cuts it out and replaces the original sequence with a new sequence. Guide RNA (gRNA) helps to navigate the CRISPR/Cas9 complex in order to target only the specific sequence.

CRISPR/Cas9 represents a valuable tool in gene editing and becomes even more popular in therapy, especially of cancer and other disease involving genetic defects (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315587/).

Picture: CRISPR/Cas9 induced DNA double-strand break.

Highlights:

  • Double nickase plasmids
  • CRISPR/dCas9 activation plasmids
  • CRISPR/dCas9 lentiviral activation particles
  • CRISPR/Cas9 plasmids
  • HDR plasmids
  • CRE vector
Set Descending Direction

113845 items

per page
  1. Amd2 CRISPR Activation Plasmid (m2)
    Amd2 CRISPR Activation Plasmid (m2)
    Price is loading...
    Sku SACSC-437220-ACT-2
    Manufact. Skusc-437220-ACT-2
    Packaging Unit20 µg
  2. Amd2 CRISPR Activation Plasmid (m)
    Amd2 CRISPR Activation Plasmid (m)
    Price is loading...
    Sku SACSC-437220-ACT
    Manufact. Skusc-437220-ACT
    Packaging Unit20 µg
  3. Amd2 CRISPR/Cas9 KO Plasmid (m)
    Amd2 CRISPR/Cas9 KO Plasmid (m)
    Price is loading...
    Sku SACSC-437220
    Manufact. Skusc-437220
    Packaging Unit20 µg
  4. ZNF483 CRISPR Activation Plasmid (m2)
    ZNF483 CRISPR Activation Plasmid (m2)
    Price is loading...
    Sku SACSC-437219-ACT-2
    Manufact. Skusc-437219-ACT-2
    Packaging Unit20 µg
  5. ZNF483 CRISPR Activation Plasmid (m)
    ZNF483 CRISPR Activation Plasmid (m)
    Price is loading...
    Sku SACSC-437219-ACT
    Manufact. Skusc-437219-ACT
    Packaging Unit20 µg
  6. ZNF483 CRISPR/Cas9 KO Plasmid (m)
    ZNF483 CRISPR/Cas9 KO Plasmid (m)
    Price is loading...
    Sku SACSC-437219
    Manufact. Skusc-437219
    Packaging Unit20 µg
  7. 9030025P20Rik CRISPR Activation Plasmid (m2)
    9030025P20Rik CRISPR Activation Plasmid (m2)
    Price is loading...
    Sku SACSC-437218-ACT-2
    Manufact. Skusc-437218-ACT-2
    Packaging Unit20 µg
  8. 9030025P20Rik CRISPR Activation Plasmid (m)
    9030025P20Rik CRISPR Activation Plasmid (m)
    Price is loading...
    Sku SACSC-437218-ACT
    Manufact. Skusc-437218-ACT
    Packaging Unit20 µg
  9. 9030025P20Rik CRISPR/Cas9 KO Plasmid (m)
    9030025P20Rik CRISPR/Cas9 KO Plasmid (m)
    Price is loading...
    Sku SACSC-437218
    Manufact. Skusc-437218
    Packaging Unit20 µg
  10. Ly-6C CRISPR Activation Plasmid (m2)
    Ly-6C CRISPR Activation Plasmid (m2)
    Price is loading...
    Sku SACSC-437217-ACT-2
    Manufact. Skusc-437217-ACT-2
    Packaging Unit20 µg
Set Descending Direction

113845 items

per page