CRISPR

CRISPR

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) are segments of short, regularly placed palindromic nucleotide repetitions. CAS (CRISPR-Associated Protein) is a CRISPR-associated nuclease enabling controlled DNA cleavage.

CRISPR/Cas9 systems allow for targeted gene editing. Briefly, aCRISPR/Cas9 complex binds to a specific DNA sequence, cuts it out and replaces the original sequence with a new sequence. Guide RNA (gRNA) helps to navigate the CRISPR/Cas9 complex in order to target only the specific sequence.

CRISPR/Cas9 represents a valuable tool in gene editing and becomes even more popular in therapy, especially of cancer and other disease involving genetic defects (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315587/).

Picture: CRISPR/Cas9 induced DNA double-strand break.

Highlights:

  • Double nickase plasmids
  • CRISPR/dCas9 activation plasmids
  • CRISPR/dCas9 lentiviral activation particles
  • CRISPR/Cas9 plasmids
  • HDR plasmids
  • CRE vector
Set Descending Direction

113845 items

per page
  1. TIGIT CRISPR/Cas9 Lentivirus (Integrating)
    TIGIT CRISPR/Cas9 Lentivirus (Integrating)
    Price is loading...
    Sku BPS78058
    Manufact. Sku78058
    Packaging Unit500 µl x 2
  2. PD-L1 CRISPR/Cas9 Lentivirus (Integrating)
    PD-L1 CRISPR/Cas9 Lentivirus (Integrating)
    Price is loading...
    Sku BPS78057
    Manufact. Sku78057
    Packaging Unit500 µl x 2
  3. CD47 CRISPR/Cas9 Lentivirus (Integrating)
    CD47 CRISPR/Cas9 Lentivirus (Integrating)
    Price is loading...
    Sku BPS78056
    Manufact. Sku78056
    Packaging Unit500 µl x 2
  4. TCR CRISPR/Cas9 Lentivirus (Integrating)
    TCR CRISPR/Cas9 Lentivirus (Integrating)
    Price is loading...
    Sku BPS78055
    Manufact. Sku78055
    Packaging Unit500 µl x 2
  5. CTLA4 CRISPR/Cas9 Lentivirus (Integrating)
    CTLA4 CRISPR/Cas9 Lentivirus (Integrating)
    Price is loading...
    Sku BPS78054
    Manufact. Sku78054
    Packaging Unit500 µl x 2
  6. LAG3 CRISPR/Cas9 Lentivirus (Integrating)
    LAG3 CRISPR/Cas9 Lentivirus (Integrating)
    Price is loading...
    Sku BPS78053
    Manufact. Sku78053
    Packaging Unit500 µl x 2
  7. PD-1 CRISPR/Cas9 Lentivirus (Integrating)
    PD-1 CRISPR/Cas9 Lentivirus (Integrating)
    Price is loading...
    Sku BPS78052
    Manufact. Sku78052
    Packaging Unit500 µl x 2
  8. AP4A Hydrolase CRISPR Activation Plasmid (r2)
    AP4A Hydrolase CRISPR Activation Plasmid (r2)
    Price is loading...
    Sku SACSC-437371-ACT-2
    Manufact. Skusc-437371-ACT-2
    Packaging Unit20 µg
  9. AP4A Hydrolase CRISPR Activation Plasmid (r)
    AP4A Hydrolase CRISPR Activation Plasmid (r)
    Price is loading...
    Sku SACSC-437371-ACT
    Manufact. Skusc-437371-ACT
    Packaging Unit20 µg
  10. AP4A Hydrolase CRISPR/Cas9 KO Plasmid (r)
    AP4A Hydrolase CRISPR/Cas9 KO Plasmid (r)
    Price is loading...
    Sku SACSC-437371
    Manufact. Skusc-437371
    Packaging Unit20 µg
Set Descending Direction

113845 items

per page