CRISPR

CRISPR

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) are segments of short, regularly placed palindromic nucleotide repetitions. CAS (CRISPR-Associated Protein) is a CRISPR-associated nuclease enabling controlled DNA cleavage.

CRISPR/Cas9 systems allow for targeted gene editing. Briefly, aCRISPR/Cas9 complex binds to a specific DNA sequence, cuts it out and replaces the original sequence with a new sequence. Guide RNA (gRNA) helps to navigate the CRISPR/Cas9 complex in order to target only the specific sequence.

CRISPR/Cas9 represents a valuable tool in gene editing and becomes even more popular in therapy, especially of cancer and other disease involving genetic defects (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315587/).

Picture: CRISPR/Cas9 induced DNA double-strand break.

Highlights:

  • Double nickase plasmids
  • CRISPR/dCas9 activation plasmids
  • CRISPR/dCas9 lentiviral activation particles
  • CRISPR/Cas9 plasmids
  • HDR plasmids
  • CRE vector
Set Descending Direction

113845 items

per page
  1. SSXB6 CRISPR/Cas9 KO Plasmid (m)
    SSXB6 CRISPR/Cas9 KO Plasmid (m)
    Price is loading...
    Sku SACSC-437154
    Manufact. Skusc-437154
    Packaging Unit20 µg
  2. MYH7B CRISPR Activation Plasmid (m2)
    MYH7B CRISPR Activation Plasmid (m2)
    Price is loading...
    Sku SACSC-437153-ACT-2
    Manufact. Skusc-437153-ACT-2
    Packaging Unit20 µg
  3. MYH7B CRISPR Activation Plasmid (m)
    MYH7B CRISPR Activation Plasmid (m)
    Price is loading...
    Sku SACSC-437153-ACT
    Manufact. Skusc-437153-ACT
    Packaging Unit20 µg
  4. MYH7B CRISPR/Cas9 KO Plasmid (m)
    MYH7B CRISPR/Cas9 KO Plasmid (m)
    Price is loading...
    Sku SACSC-437153
    Manufact. Skusc-437153
    Packaging Unit20 µg
  5. ZFP442 CRISPR Activation Plasmid (m2)
    ZFP442 CRISPR Activation Plasmid (m2)
    Price is loading...
    Sku SACSC-437152-ACT-2
    Manufact. Skusc-437152-ACT-2
    Packaging Unit20 µg
  6. ZFP442 CRISPR Activation Plasmid (m)
    ZFP442 CRISPR Activation Plasmid (m)
    Price is loading...
    Sku SACSC-437152-ACT
    Manufact. Skusc-437152-ACT
    Packaging Unit20 µg
  7. ZFP442 CRISPR/Cas9 KO Plasmid (m)
    ZFP442 CRISPR/Cas9 KO Plasmid (m)
    Price is loading...
    Sku SACSC-437152
    Manufact. Skusc-437152
    Packaging Unit20 µg
  8. FBXW28 CRISPR Activation Plasmid (m2)
    FBXW28 CRISPR Activation Plasmid (m2)
    Price is loading...
    Sku SACSC-437151-ACT-2
    Manufact. Skusc-437151-ACT-2
    Packaging Unit20 µg
  9. FBXW28 CRISPR Activation Plasmid (m)
    FBXW28 CRISPR Activation Plasmid (m)
    Price is loading...
    Sku SACSC-437151-ACT
    Manufact. Skusc-437151-ACT
    Packaging Unit20 µg
  10. FBXW28 CRISPR/Cas9 KO Plasmid (m)
    FBXW28 CRISPR/Cas9 KO Plasmid (m)
    Price is loading...
    Sku SACSC-437151
    Manufact. Skusc-437151
    Packaging Unit20 µg
Set Descending Direction

113845 items

per page