CRISPR

CRISPR

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) are segments of short, regularly placed palindromic nucleotide repetitions. CAS (CRISPR-Associated Protein) is a CRISPR-associated nuclease enabling controlled DNA cleavage.

CRISPR/Cas9 systems allow for targeted gene editing. Briefly, aCRISPR/Cas9 complex binds to a specific DNA sequence, cuts it out and replaces the original sequence with a new sequence. Guide RNA (gRNA) helps to navigate the CRISPR/Cas9 complex in order to target only the specific sequence.

CRISPR/Cas9 represents a valuable tool in gene editing and becomes even more popular in therapy, especially of cancer and other disease involving genetic defects (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315587/).

Picture: CRISPR/Cas9 induced DNA double-strand break.

Highlights:

  • Double nickase plasmids
  • CRISPR/dCas9 activation plasmids
  • CRISPR/dCas9 lentiviral activation particles
  • CRISPR/Cas9 plasmids
  • HDR plasmids
  • CRE vector
Set Descending Direction

113845 items

per page
  1. Unc18-2 CRISPR/Cas9 KO Plasmid (r)
    Unc18-2 CRISPR/Cas9 KO Plasmid (r)
    Price is loading...
    Sku SACSC-437364
    Manufact. Skusc-437364
    Packaging Unit20 µg
  2. cGAS CRISPR Activation Plasmid (m2)
    cGAS CRISPR Activation Plasmid (m2)
    Price is loading...
    Sku SACSC-437363-ACT-2
    Manufact. Skusc-437363-ACT-2
    Packaging Unit20 µg
  3. cGAS CRISPR Activation Plasmid (m)
    cGAS CRISPR Activation Plasmid (m)
    Price is loading...
    Sku SACSC-437363-ACT
    Manufact. Skusc-437363-ACT
    Packaging Unit20 µg
  4. cGAS CRISPR/Cas9 KO Plasmid (m)
    cGAS CRISPR/Cas9 KO Plasmid (m)
    Price is loading...
    Sku SACSC-437363
    Manufact. Skusc-437363
    Packaging Unit20 µg
  5. NAB2 CRISPR Activation Plasmid (r2)
    NAB2 CRISPR Activation Plasmid (r2)
    Price is loading...
    Sku SACSC-437362-ACT-2
    Manufact. Skusc-437362-ACT-2
    Packaging Unit20 µg
  6. NAB2 CRISPR Activation Plasmid (r)
    NAB2 CRISPR Activation Plasmid (r)
    Price is loading...
    Sku SACSC-437362-ACT
    Manufact. Skusc-437362-ACT
    Packaging Unit20 µg
  7. NAB2 CRISPR/Cas9 KO Plasmid (r)
    NAB2 CRISPR/Cas9 KO Plasmid (r)
    Price is loading...
    Sku SACSC-437362
    Manufact. Skusc-437362
    Packaging Unit20 µg
  8. LDH-A CRISPR Activation Plasmid (r2)
    LDH-A CRISPR Activation Plasmid (r2)
    Price is loading...
    Sku SACSC-437361-ACT-2
    Manufact. Skusc-437361-ACT-2
    Packaging Unit20 µg
  9. LDH-A CRISPR Activation Plasmid (r)
    LDH-A CRISPR Activation Plasmid (r)
    Price is loading...
    Sku SACSC-437361-ACT
    Manufact. Skusc-437361-ACT
    Packaging Unit20 µg
  10. LDH-A CRISPR/Cas9 KO Plasmid (r)
    LDH-A CRISPR/Cas9 KO Plasmid (r)
    Price is loading...
    Sku SACSC-437361
    Manufact. Skusc-437361
    Packaging Unit20 µg
Set Descending Direction

113845 items

per page