Formulation: A solid
Purity: ≥95%
Formula Markup: C12H2Cl6O
Formula Weight: 374,9
Shelf life (days): 1460
CAS Number: 57117-44-9
Notes: 1,2,3,6,7,8-Hexachlorodibenzofuran is a dioxin-like polychlorinated dibenzofuran (PCDF).{51242} It induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 1.47 and 1.24 nM, respectively).{69319} It reduces weight, induces thymic atrophy, and induces the expression of genes encoding the cytochrome P450 (CYP) isoform CYP1A1 and 4-chlorobiphenyl hydroxylase in rats (ED50s = 3.2, 0.9, 0.35, and 0.21 µmol/kg, respectively).{64924} It has been found in the soil near municipal waste incinerators, in freshwater fish, and in human breastmilk.{51242,69320,69321}