Formulation: A solid
Formal Name: 2′-deoxy-adenosine 5′-(trihydrogen diphosphate), P′→5-ester with D-ribose, disodium salt
Purity: ≥98%
Formula Markup: C15H21N5O13P2 • 2Na
Formula Weight: 587,3
Shelf life (days): 1460
Notes: 2'-Deoxyadenosine-5'-O-diphosphoribose is a transient receptor potential melastatin 2 (TRPM2) agonist.{51245} It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human TRPM2 when used at a concentration of 30 µM. 2'-Deoxyadenosine-5'-O-diphosphoribose has been found in Jurkat cells. It is also a substrate of nucleotide triphosphate diphosphatase 9 (NUDT9), a mitochondrial enzyme involved in hydrolyzing pyrophosphates.{51246}